In 1942, six people destroyed Anna Matheson’s family. Twelve years later, she’s ready for retribution. Under false pretenses, Anna has lured those responsible for her family’s downfall onto a luxury train from Philadelphia to Chicago, an overnight journey of 13 hours. Her goal? Confront the people who have wronged her, get them to confess their crimes, and deliver them into the hands of authorities waiting at the end of the line. But Anna’s plan is quickly derailed by the murder of one of the passengers. As the train barrels through the night, it becomes clear that someone else on board is enacting their own form of revenge --- and they won’t stop until everyone else is dead.