It is 1486, and Venice is a wealthy, opulent center for trade. Orsola Rosso is the eldest daughter in a family of glassblowers on Murano, the island revered for the craft. As a woman, she is not meant to work with glass --- but she has the hands for it, the heart and a vision. When her father dies, she teaches herself to make glass beads in secret, and her work supports the Rosso family fortunes. Skipping like a stone through the centuries, in a Venice where time moves as slowly as molten glass, we follow Orsola and her family as they live through creative triumph and heartbreaking loss --- from a plague devastating Venice to Continental soldiers stripping its palazzos bare, from the domination of Murano and its maestros to the transformation of the city of trade into a city of tourists.