Dr. Marina Singh is sent to Brazil to track down her former mentor, who seems to have disappeared in the Amazon while working on what is destined to be a valuable new drug. She also hopes to find answers to questions about another friend's death, the state of her company's future, and her own past.

A literary sensation, this extraordinarily candid novel about the experience of growing up female in America will strike a nerve in readers of all ages.

It is 1968. Lynnie, a young white woman with a developmental disability, and Homan, an African American deaf man, are locked away in an institution. Deeply in love, they escape and find refuge. But the couple is not alone --- Lynnie has just given birth to a baby girl.

Daelyn Rice is broken beyond repair, and after several suicide attempts, she's determined to get her death right. So she starts visiting a website for "completers." There, Daelyn blogs about her life, uncovering a history of bullying that goes back to kindergarten. When she's not on the Web, Daelyn is at her private school, where she's known as the freak who doesn't talk.

Bethia Mayfield lives among pioneers and Puritans of the 17th century. She yearns for an education, but her gender forbids it. At 12 she encounters Caleb, the Native American son of a chieftain, and the two forge a secret friendship. When Caleb goes to Cambridge to study Latin and Greek, Bethia finds herself there too --- but she is indentured as a housekeeper.

When 17-year-old Jamie arrives on the idyllic island of Little Bly to work as a summer au pair, she is stunned to learn of the horror that precedes her. Seeking the truth surrounding a young couple's tragic deaths, Jamie discovers that she herself looks shockingly like the dead girl --- and that she has a disturbing ability to sense the two ghosts. As the secrets of the house wrap tighter around her, Jamie must navigate the increasingly blurred divide between the worlds of the living and the dead.