Out of money and with little to show for his art school education, John-Calum Macleod takes the ferry back home to the Isle of Harris in the Outer Hebrides. He returns to the two pillars of his childhood: his father John, a sheep farmer, tweed weaver and lay preacher in the local Presbyterian church, and his maternal grandmother Ella, whose steady warmth helped Cal weather the sudden departure of his mother. Cal privately wonders if any lonely men might be found on the barren hillsides of home, while John is dismayed by his son’s seeming unwillingness to be Saved. But Cal isn't the only one in the croft house who is keeping secrets. As lambing season turns to shearing season, the threads holding the community together become increasingly frayed, and nothing will remain as it was before.

Artie Dam is living a double life. He spends his days teaching history to 11th graders. He goes to holiday parties with his wife of three decades, makes small talk with neighbors, and, on weekends, takes his sailboat out on the beautiful Massachusetts Bay. But inside, Artie is plagued by feelings of isolation. He looks out at a world gone mad --- at himself and the people around him --- and turns a question over and over in his mind: How is it that we know so little about one another, even those closest to us? And then, one day, Artie learns that life has been keeping a secret from him, one that threatens to upend his entire world. Once he learns it, he is forced to chart a new course, to reconsider the relationships he holds most dear --- and to make peace with the mysteries at the heart of our existence.

Christmas, 1857. America's future is precarious; civil war looms on the horizon. After her abolitionist husband is murdered in the lawless Kansas Territory, Lidie Newton returns, in mourning, to her hometown of Quincy, Illinois. But her sisters have little comfort to offer, and Lidie is haunted by the memories of her failures --- until she takes an interest in her niece, Annie. Annie becomes an actress at the local theater, and when she is offered the opportunity to perform abroad, she decides to run away. But travel is dangerous for a young unmarried woman, so Lidie, armed with her pistol and her wit, goes with her. The two women embark on a perilous journey across the Atlantic. Once they arrive in Liverpool, they vanish into new roles in the household of Annie's benefactor, Mr. Mallory Cunningham. But will either of them be content with her new lot in life?

High school English teacher Polly Goodman can talk about everything and anything with the women in her book club, which is why they’ve become her closest friends and, along with her veterinarian husband, the bedrock of her life. Her students, her fraught relationship with her mother, her struggles with IVF --- Polly’s book club friends have heard about it all. But when they give Polly an ancestry test kit as a joke, the results match her with a stranger. It is clear to Polly that this match is a mistake, but still she cannot help but comb through her family history for answers. Then, when it seems that the book club circle of four will become three, Polly learns how friendships can change your life in the most profound ways.

Radically open-minded, formidably strong, and unusually clear-eyed about herself and others, Evelyn Bednarz has always been a misfit. She's easily bored, unsuited to life at school, asks odd questions about faith and time, and sees through conventions that others take for granted. Seeking to be true to herself, she hitchhikes across the American West taking odd jobs. In distant Tibet, another life unfolds as remote from Evelyn’s as can be: the life of a boy named Tsering, raised as a Buddhist monk in the mountains of Tibet, who eventually becomes a high lama. And yet, their lives are strangely linked --- as Evelyn discovers when a trio of Buddhist lamas show up at her door to announce that her five-year-old son, Cliff, is the seventh reincarnation of the illustrious Norbu Rinpoche, recently deceased. The lamas’ visit sets off a family crisis and a media firestorm over Cliff’s future.

In the fall of her senior year of college, our narrator meets two star students from her 17th-Century Lit class: Sam and Yash. The boys invite her into their intoxicating world of academic fervor, rapid-fire banter and raucous card games. They nickname her Jordan, and she quickly discovers the pleasures of friendship, love and her own intellectual ambition. But youthful passion is unpredictable, and soon she finds herself at the center of a charged and intricate triangle. As graduation comes and goes, choices made will alter these three lives forever. Decades later, the vulnerable days of Jordan's youth seem comfortably behind her. But when a surprise visit and unexpected news bring the past crashing into the present, she returns to a world she left behind and must confront the decisions and deceptions of her younger self.

2014: Renowned poet Francis Blundy honors his wife’s birthday by reading aloud a new poem dedicated to her, “A Corona for Vivien.” Little does anyone gathered around the candlelit table know that for generations to come, people will speculate about the message of this poem, the only copy of which goes missing. 2119: Just over 100 years in the future, much of the planet has been submerged by rising seas following a catastrophic nuclear accident. Thomas Metcalfe, a lonely scholar and researcher, longs for the early 21st century as he chases the ghost of one poem, “A Corona for Vivien.” When he stumbles across a clue that may lead to the elusive poem’s discovery, a story is revealed of a brutal crime that destroys his assumptions about people he thought he knew intimately well.

The Bradford-Shmulkin family is falling apart as the pressures of life in an unstable America are fraying their bonds. There's Daddy, a struggling, cash-thirsty editor whose Russian heritage gives him a surprising new currency in the upside-down world of 21st-century geopolitics; his wife, Anne Mom, a progressive, underfunded blue blood from Boston who's barely holding the household together; their son, Dylan, whose blond hair and Mayflower lineage provide him pride of place in the newly forming American political order; and young Vera, half-Jewish, half-Korean and wholly original. Vera wants only three things in life: to make a friend at school; for Daddy and Anne Mom to stay together; and to meet her birth mother, Mom Mom, who at last will tell Vera the secret of who she really is and how to ensure love's survival in this great, mad, imploding world.

Abe Winter and Ruth Warneke were never meant to be together --- at least if you ask Ruth. Yet their catastrophic blind date in college evolved into a 70-year marriage and a life on a farm on Bainbridge Island with their hens and beloved Labrador, Megs. Through the years, the Winters have fallen in and out of lockstep, and from their haunting losses and guarded secrets, a dependable partnership has been forged. But when Ruth’s loose tooth turns out to be something much more malicious, the beautiful, reliable life they’ve created together comes to a crisis. As Ruth struggles with her crumbling independence, Abe must learn how to take care of her while their three living children question his ability to look after his wife. And once again, the couple has to reconfigure how to be there for each other.

Anna Williams-Bonner has taken care of business. That is to say, she’s taken care of her husband, bestselling novelist Jacob Finch Bonner, and laid to rest those anonymous accusations of plagiarism that so tormented him. Now she is living the contented life of a literary widow, enjoying her husband’s royalty checks in perpetuity. But for the second time in her life, a work of fiction intercedes, and this time it’s her own debut novel, The Afterword. When Anna publishes her book and indulges in her own literary acclaim, she begins to receive excerpts of a novel she never expected to see again, a novel that should no longer exist. Someone out there knows far too much: about her late brother, her late husband, and just possibly...Anna herself. What does this person want, and what are they prepared to do?