In a little town in the south of France in the 1960s, a dazzling encounter with Love itself changes the life of infant orphan Marie-Jeanne forever. As a girl, Marie-Jeanne realizes that she can see the marks Love has left on the people around her --- tiny glowing lights on the faces and hands that shimmer more brightly when the one meant for them is near. Before long, Marie-Jeanne is playing matchmaker. As she grows up, Marie-Jeanne helps her foster father, Francis, begin a mobile library that travels throughout the many small mountain towns in the region of Nyons. She finds herself bringing soulmates together every place they go --- and there are always books that play a pivotal role in that quest. However, the only person that Marie-Jeanne can’t seem to find a soulmate for is herself.

Henri Skinner is a hardened ex-war reporter on the run from his past. On his way to see his son, Sam, for the first time in years, Henri collides with oncoming traffic. He is rushed to a nearby hospital where he floats, comatose, between dreams. After the accident, Sam --- a 13-year-old synesthete with an IQ of 144 and an appetite for science fiction --- waits by his father’s bedside every day. There he meets Eddie Tomlin, a woman forced to confront her love for Henri after all these years, and 12-year-old Madelyn Zeidler, a coma patient like Henri and the sole survivor of a traffic accident that killed her family. As these four very different individuals fight --- for hope, for patience, for life --- they are bound together inextricably, facing the ravages of loss and first love side by side.

Marianne is stuck in a loveless, unhappy marriage. After 41 years, she has reached her limit, and one evening in Paris she decides to take action. Following a dramatic moment on the banks of the Seine, Marianne leaves her life behind and sets out for the coast of Brittany, also known as “the end of the world.” Here she meets a cast of colorful and unforgettable locals who surprise her with their warm welcome and the natural ease they all seem to have, taking pleasure in life’s small moments. And, as the parts of herself she had long forgotten return to her in this new world, Marianne learns it’s never too late to begin the search for what life should have been all along.

From his floating bookstore in a barge on the Seine, Monsieur Perdu prescribes novels for the hardships of life. Using his intuitive feel for the exact book a reader needs, Perdu mends broken hearts and souls. The only person he can't seem to heal through literature is himself; he's still haunted by heartbreak after his great love disappeared. She left him with only a letter, which he has never opened. After Perdu is finally tempted to read the letter, he departs on a mission to the south of France, hoping to make peace with his loss and discover the end of the story.