ER nurse Macy Wynn has finally located the fellow foster child she loves like a sister, but the girl is in deep trouble. Macy is determined to help, no matter what it takes. Her motto is to “make it happen” in any situation life throws at her --- even when she butts heads with an idealistic cop. Deputy Fletcher Holt believes in a higher plan, the fair outcome. Now he’s been yanked from Houston, his mother is battling cancer, and he’s attracted to a strong-willed nurse who could be the target of a brutal sniper. When everything goes wrong, where do they put their trust?

Nurse Lauren Barclay put her life on hold to keep a watchful eye on her troubled sister. But that means confronting the brooding physician assistant who caused painful turmoil in her family. PA and single parent Elijah Landry is determined to protect his disabled brother and make peace with Lauren. He wants that and so much more. But as Lauren and Eli draw closer, a powerful hurricane roars toward Houston. Can hope weather the storm?

Tired of running from her past, nurse Kate Callison intends to become Austin Grace Hospital’s permanent ER director and make Texas her home. Despite staff friction, she’s moving ahead. Then unthinkable tragedy wraps the ER in crime tape, bringing swarms of media, legal chaos --- and a search-and-rescue hero who seems determined to meddle in her life.

Sidelined by injuries from a vicious assault, chaplain Riley Hale is determined to return to her former duties as an ER nurse. To prove herself, she volunteers at a controversial urban free clinic. Dr. Jack Travis will fight the community’s efforts to shut the clinic's doors, even if he must use Riley’s influential family name to make it happen. As Riley strives to regain her skills, Jack finds that she shares his compassion --- and stirs his lonely heart.