Girls are disappearing in Botswana. The rumor is they're being harvested for muti, a witch doctor's potion traditionally derived from plants and animals --- and which, some believe, can be made more potent by adding human remains. Detective David "Kubu" Bengu joins the investigation with the police force's newest detective --- and only woman --- Samantha Khama, for whom the case is personal.

Soon one girl's father, convinced that his daughter's death is linked to the recent popularity of a political candidate, takes the law into his own hands. After the father flees, what Kubu and Samantha find in the politician's home confirms their worst fears: muti containing human DNA is real.

Now Kubu and Samantha are thrust into a harrowing race to stop a serial killer or killers --- and those who would pay for their special, lethal muti.