Four years after a tragic mission decimated his team, Cole "Tox" Russell has been disavowed by the United States. But when a dormant, centuries-old disease is unleashed, he is lured back into action. Tox and his former Special Forces team regroup to work with FBI deception expert Kasey Cortes and fiery archaeologist Tzivia Khalon to search the globe for answers --- and a cure. As the mission leads from one continent to another, it becomes clear they're not just fighting a plague but battling an ancient secret society whose true goals remain hidden. Tox and his team soon realize that their sole chance might be to reach back through centuries of silence to find the only answer that can save them all.