The invite promised to celebrate “the greatest artist of the century.” Blanche Devereaux’s passionate dalliances are as plentiful as hot Southern nights, and surely one can’t be expected to remember all of one’s suitors. But when the Girls disembark the party’s ferry at a small Biscayne Bay island and meet their secretive host, the memories come flooding back: she a Radio City Rockette in her 20s, he the poor artist who could offer her nothing but his love. Fate drove them apart, but Declan, now the famous artist El Toro, professes that Blanche has always been his muse. A tropical storm knocks power out across the island, and when Declan is found dead the next morning, all eyes are on Blanche. Trapped at the estate with the other guests, the Girls must band together to find the true killer.

Rose’s cousin is eloping to Miami, and Rose is playing host. If she can't balance the groom’s family’s snobbery against the traditional St. Olaf wedding week guidelines, her hometown may never accept her cousin again! Dorothy quickly realizes she needs a date with whom she can exchange wedding-related wisecracks. Turning to a newfangled VHS dating service, she believes she’s found the ideal conversationalist. Unfortunately, what looks good on TV can actually be a total jerk in real life. It seems she’ll just have to enjoy the company of Sophia, Blanche, and whomever Blanche has targeted for a hookup. But then Dorothy’s date is found dead --- face-planted in an otherwise scrumptious-looking cheesecake. The four besties must ID the real killer, get the should-be-happy couple down the aisle, and make sure nobody from St. Olaf gets lost in the wilds of Miami.