Deep beneath the ground outside of Geneva, where CERN’s Large Hadron Collider smashes subatomic particles at breathtaking speeds, a startling discovery is made when the tunnel is down for maintenance: the body of Howard Anderby, a brilliant and recently arrived young physicist, who appears to have been irradiated by the collider. But security shows no evidence of him entering the tunnel, and the lab’s video surveillance is sorely lacking. Eager to keep the death under wraps until more is known, CERN brings in private investigator Sabine Leroux, who has her own ties to the lab’s administration --- and more than a passing interest in particle physics. Meanwhile, Howard’s colleague and budding love interest, Eve, determines to reconcile what she knew of Howard with his gruesome fate, wondering if she could have done something to stop it.

Just days after mathematician and family patriarch Isaac Severy dies of an apparent suicide, his adopted granddaughter Hazel, owner of a struggling bookstore, receives a letter from him by mail. In it, Isaac alludes to a secretive organization that is after his final bombshell equation, and he charges Hazel with safely delivering it to a trusted colleague. But first, she must find where the equation is hidden. While in Los Angeles for Isaac’s funeral, Hazel realizes she’s not the only one searching for his life’s work, and that the equation’s implications have potentially disastrous consequences for the extended Severy family, a group of dysfunctional geniuses unmoored by the sudden death of their patriarch.