It’s a steamy, restless end of the school year in New Orleans. Sister Holiday is staying busy with her music classes and preparing for her permanent vow ceremony, a pivotal moment in her journey of faith. But when one of her favorite students is found dead of a fentanyl overdose, Sister Holiday and her partner-in-PI, Magnolia Riveaux, are launched on a mission to track down the drug dealers. As students continue to fall prey to this sinister drug under her watch, Sister Holiday becomes more and more desperate to stop this epidemic. All the while, she must contend with her own past with addiction, a demon that is never too far.

Tattooed from her neck to her toes and sporting a gold tooth as sharp as her wisecracks, Sister Holiday struggles to stay on the righteous path. Never one to make things easy for herself, she’s committed to taking her permanent vows with the Sisters of the Sublime Blood and joining former fire inspector Magnolia Riveaux’s latest venture, Redemption Detective Agency --- both in service of satisfying her eternal quest for answers. When Sister Holiday and Riveaux set out to bust a philandering husband, they instead find the body of a priest floating in the swollen Mississippi River. It’s significantly more gruesome than their original mission, but Sister Holiday feels called on by God to hunt down the murderer and keep her community safe.

When Saint Sebastian’s School becomes the target of a shocking arson spree, the Sisters of the Sublime Blood and their surrounding New Orleans community are thrust into chaos. Patience is a virtue, but punk rocker turned nun Sister Holiday isn’t satisfied to just wait around for officials to return her home and sanctuary to its former peace, instead deciding to unveil the mysterious attacker herself. Her investigation leads her down a twisty path of suspicion and secrets, turning her against colleagues, students and even fellow Sisters along the way. And to piece together the clues of this high-stakes mystery, she must at last reckon with the sins of her own past.