In 1874, in the wake of the War, erasure, trauma and namelessness haunt civilians and veterans, renegades and wanderers, freedmen and runaways. Twelve-year-old ConaLee, the adult in her family for as long as she can remember, finds herself on a buckboard journey with her mother, Eliza, who hasn’t spoken in more than a year. They arrive at the Trans-Allegheny Lunatic Asylum in West Virginia, delivered to the hospital’s entrance by a war veteran who has forced himself into their world. There, far from family, a beloved neighbor, and the mountain home they knew, they try to reclaim their lives. They get swept up in the life of the facility --- the mysterious man they call the Night Watch; the orphan child called Weed; the fearsome woman who runs the kitchen; and the remarkable doctor at the head of the institution.

Weeks after meeting a chivalrous, elegant man named Harry Powers, Asta Eicher and her three children are dead. Journalist Emily Thornhill becomes deeply invested in understanding what happened, and allies herself with a banker who is wracked by guilt for not saving Asta. She goes to West Virginia to cover the murder trial and to investigate the story herself, accompanied by a charming and unconventional photographer who is equally drawn to the case.