The year is 2041, and it's a dangerous time to be a woman driving across the United States alone. But Kelly desperately needs to get back to her daughter, who she left seven years ago for a cause that she's no longer sure she believes in. Almost 40 years later, another mother, Ava, and her daughter Brook are on the run as well, from the climate change relief program known as The Inside Project, where they've spent the past 22 years being treated as lab rats. At the same time, way up North, weather conditions continue to worsen and a settlement departs in search of greener pastures, leaving behind only two members, drawn together by a circumstance and a mystery they are destined to unravel together.

The year is 2050. Ava and her girlfriend live in what's left of Brooklyn. Although they love each other, it's hard to find happiness while the effects of climate change rapidly eclipse their world. Soon, it won't be safe outside at all. The only people guaranteed survival are the ones whose applications are accepted to The Inside Project, a series of weather-safe, city-sized structures around the world. When Ava is accepted to live Inside and her girlfriend isn’t, she’s forced to go alone. But her heartbreak is quickly replaced with a feeling of belonging: Inside seems like it’s the safe space she’s been searching for...most of the time. Other times she can’t shake the feeling that something is deeply off.