Years ago, Shawn Eagle and Billy Stafford created a revolutionary computer called Eagle Logic. But they parted ways following a major falling-out. Now Billy is beset by poverty and addiction, and Shawn is the most famous man in the world. Unable to let the past be forgotten, Shawn decides to resurrect his and Billy’s biggest failure: a next-generation computer program named Nellie that can control a house’s every function. He decides to set it up in the abandoned mansion they worked near all those years ago. But something about Nellie isn’t right --- and the reconstruction of the mansion is plagued by accidental deaths. Shawn is forced to bring Billy back, despite their longstanding mutual hatred, to discover and destroy the evil that lurks in the source code.

The only thing more terrifying than millions of spiders is the realization that those spiders work as one. But among the government, there is dissent: Do we try to kill all of the spiders, or do we gamble on Professor Guyer’s theory that we need to kill only the queens? For President Stephanie Pilgrim, it’s an easy answer. She’s gone as far as she can --- more than two dozen American cities hit with tactical nukes --- and the only answer is to believe in Professor Guyer. Unfortunately, Ben Broussard and the military men who follow him don’t agree, and Pilgrim, Guyer and the loyal members of the government have to flee, leaving the question: What’s more dangerous, the spiders or ourselves?

First, there was the black swarm that swallowed a man whole, the suspicious seismic irregularities in India that confounded scientists, the nuclear bomb China dropped on its own territory without any explanation. Then, scientist Melanie Guyer's lab received a package containing a mysterious egg sac; little did Dr. Guyer know that, almost overnight, Earth would be consumed by previously dormant spiders that suddenly wanted out. Now, tens of millions of people around the world are dead. According to Dr. Guyer, the crisis may soon be over. But in Japan, a giant, glowing egg sac gives a shocking preview of what is to come, even as survivors in Los Angeles panic and break the quarantine zone.

Deep in the jungle of Peru, where so much remains unknown, a black, skittering mass devours an American tourist whole. Thousands of miles away, an FBI agent investigates a fatal plane crash in Minneapolis and makes a gruesome discovery. Unusual seismic patterns register in a Kanpur, India earthquake lab, confounding the scientists there. During the same week, the Chinese government “accidentally” drops a nuclear bomb in an isolated region of its own country. As these incidents begin to sweep the globe, a mysterious package from South America arrives at a Washington, D.C. laboratory. The world is on the brink of an apocalyptic disaster. An ancient species, long dormant, is now very much awake.