Four freshmen arrive at college from completely different worlds: Lainey, a California party girl with a flair for drama; Tyson, a brilliant scholar and an aspiring lawyer from Washington, D.C.; Summer, an ambitious, recruited athlete from the Midwest; and Hannah, a mild-mannered southerner. Soon after arriving on campus, they strike up a conversation in their shared dorm. As their college years fly by, the four become inseparable. But as graduation nears, their lives are forever changed after a desperate act leads to tragic consequences. They make a pact, promising to always be there for one another. Ten years later, Hannah is anticipating what should be one of the happiest moments of her life when everything is suddenly turned upside down. Calling on her closest friends, it soon becomes clear that they are all facing their own crossroads.

The Kingsley family is beloved for their military heroics and political service. In 1967, after Joseph S. Kingsley, Jr. is killed in a tragic accident, his charismatic son inherits the weight of that legacy. But despite his best intentions, Joe III has trouble meeting the expectations of a nation. Cate Cooper also grew up fatherless, and after her mother marries an abusive man, she is forced to fend for herself. After being discovered by a model scout, Cate decides that her looks may be her only ticket out of the cycle of disappointment that her mother has always inhabited. When Joe and Cate unexpectedly cross paths one afternoon, their connection is instant and intense. But can their relationship survive the glare of the spotlight and the so-called Kingsley curse?

It’s 2am on a Saturday night in the spring of 2001, and 28-year-old Cecily Gardner sits alone in a dive bar in New York’s East Village, questioning her life. Feeling lonesome and homesick for the Midwest, she wonders if she’ll ever make it as a reporter in the big city --- and whether she made a terrible mistake in breaking up with her longtime boyfriend, Matthew. As Cecily reaches for the phone to call him, she hears a guy on the barstool next to her say, “Don’t do it --- you’ll regret it.” Something tells her to listen, and over the next several hours --- and shots of tequila --- the two forge an unlikely connection. Then Grant disappears in the chaos of 9/11. Fearing the worst, Cecily spots his face on a missing-person poster, and realizes she is not the only one searching for him. Her investigative reporting instincts kick into action as she vows to discover the truth.

Nina Browning is living the good life after marrying into Nashville’s elite. Yet sometimes the middle-class small-town girl in Nina wonders if she has strayed from the person she once was. Tom Volpe is a single dad working multiple jobs while struggling to raise his headstrong daughter, Lyla. His road has been lonely, long and hard, but he finally starts to relax after Lyla earns a scholarship to Windsor Academy, Nashville’s most prestigious private school. Then one photograph, snapped in a drunken moment at a party, changes everything. At the heart of the lies and scandal, Tom, Nina and Lyla are forced together --- all questioning their closest relationships, asking themselves who they really are, and searching for the courage to live a life of true meaning.

Growing up, Josie and Meredith Garland shared a close relationship. But when tragedy strikes their family, they grow apart. Fifteen years later, Josie and Meredith are following different paths. Josie is a first grade teacher with the yearning to become a mother. Meredith is a successful attorney, married and raising a four-year-old-daughter, yet questions whether this is the life she truly desires. As the anniversary of their tragedy looms, they must confront the issues that divide them and also come to terms with their own choices.

Thirty-three-year-old Shea Rigsby has spent her entire life in Walker, Texas, too devoted to her hometown football team to leave. But when an unexpected tragedy strikes the tight-knit Walker community, Shea’s comfortable world is upended, and she begins to wonder if the life she has chosen is really enough for her. Shea discovers unsettling truths about the people and things she has always trusted most --- and is forced to confront her deepest desires, fears and secrets.

Marian Caldwell, a 36-year-old television producer, is living her dream in New York City. With a fulfilling career and a satisfying relationship, Marian has everyone convinced that her life is going just the way she wants it to be. But when Kirby Rose, an 18-year-old with a key to Marian’s past, shows up on her doorstep, everything Marian has worked so hard to keep secret pours out.