It’s 2am on a Saturday night in the spring of 2001, and 28-year-old Cecily Gardner sits alone in a dive bar in New York’s East Village, questioning her life. Feeling lonesome and homesick for the Midwest, she wonders if she’ll ever make it as a reporter in the big city --- and whether she made a terrible mistake in breaking up with her longtime boyfriend, Matthew.  As Cecily reaches for the phone to call him, she hears a guy on the barstool next to her say, “Don’t do it --- you’ll regret it.” Something tells her to listen, and over the next several hours --- and shots of tequila --- the two forge an unlikely connection. Then Grant disappears in the chaos of 9/11. Fearing the worst, Cecily spots his face on a missing-person poster, and realizes she is not the only one searching for him. Her investigative reporting instincts kick into action as she vows to discover the truth.

Nina Browning is living the good life after marrying into Nashville’s elite. Yet sometimes the middle-class small-town girl in Nina wonders if she has strayed from the person she once was. Tom Volpe is a single dad working multiple jobs while struggling to raise his headstrong daughter, Lyla. His road has been lonely, long and hard, but he finally starts to relax after Lyla earns a scholarship to Windsor Academy, Nashville’s most prestigious private school. Then one photograph, snapped in a drunken moment at a party, changes everything. At the heart of the lies and scandal, Tom, Nina and Lyla are forced together --- all questioning their closest relationships, asking themselves who they really are, and searching for the courage to live a life of true meaning.

Growing up, Josie and Meredith Garland shared a close relationship. But when tragedy strikes their family, they grow apart. Fifteen years later, Josie and Meredith are following different paths. Josie is a first grade teacher with the yearning to become a mother. Meredith is a successful attorney, married and raising a four-year-old-daughter, yet questions whether this is the life she truly desires. As the anniversary of their tragedy looms, they must confront the issues that divide them and also come to terms with their own choices.

Thirty-three-year-old Shea Rigsby has spent her entire life in Walker, Texas, too devoted to her hometown football team to leave. But when an unexpected tragedy strikes the tight-knit Walker community, Shea’s comfortable world is upended, and she begins to wonder if the life she has chosen is really enough for her. Shea discovers unsettling truths about the people and things she has always trusted most --- and is forced to confront her deepest desires, fears and secrets.

Marian Caldwell, a 36-year-old television producer, is living her dream in New York City. With a fulfilling career and a satisfying relationship, Marian has everyone convinced that her life is going just the way she wants it to be. But when Kirby Rose, an 18-year-old with a key to Marian’s past, shows up on her doorstep, everything Marian has worked so hard to keep secret pours out.