2160: It's been 10 years since the cataclysmic events of Eventide, Water City, where 99.97 percent of the human population was possessed or obliterated by Akira Kimura, Water City’s renowned scientist and Earth’s former savior. Our nameless antihero and his daughter, Ascalon, navigate through a post-apocalyptic landscape populated by barbaric Zeroes --- the permanent residents of the continent’s biggest landfill, The Great Leachate --- who cling to the ways of the old world. They live in opposition to Akira’s godlike domination of the planet. She has taken control of the population that viewed her as a god and converted them into her Gardeners, zombie-like humans who plod along to build her vision of a new world. What that world exactly entails, Ascalon is not entirely sure, but she intends to find out.

2150: Eight years after the murder of Akira Kimura, Water City’s renowned scientist and anointed “God,” the nameless antihero who tracked down Akira’s killer is no longer a detective. While his wife climbs the corporate ladder of the city’s police department, he raises their now nine-year-old daughter and occasionally takes the odd job as a bounty hunter. His domestic bliss is threatened when Ascalon’s Scar --- the mark left by Akira’s destruction of Sessho-seki, the asteroid that nearly wiped out life on Earth --- vanishes from the sky and a familiar face thought dead returns from the ocean depths to exact revenge on humanity. On a journey to the moon and back, Water City’s antihero will risk everything, including his family, to save the last of the human race.

Year 2142: Earth is 40 years past a near-collision with the asteroid Sessho-seki. Akira Kimura, the scientist responsible for eliminating the threat, has reached heights of celebrity approaching deification. But now, Akira feels her safety is under threat, so after years without contact, she reaches out to her former head of security, who has since become a police detective. When he arrives at her deep-sea home and finds Akira methodically dismembered, this detective will risk everything --- his career, his family, even his own life --- and delve back into his shared past with Akira to find her killer.