Maya, an artist, and Noah, a quantum physicist, share an insatiable curiosity about the world. But their happy marriage has a shadow over it: Serena, the child Noah had with his first wife, who died before she turned four. When Noah is invited by the Janus Project to unravel the secrets of time travel, he jumps at the opportunity. At a laboratory deep in the Texas desert, he begins participating in a dangerous experiment that could result in something he thought impossible: seeing his daughter again. Meanwhile, Maya embarks on a journey back to her own past in Japan, and to a formative lover who once shattered her heart. As Noah and Maya grapple with hope and despair, new information emerges that the experiments might not be exactly what they seem.

Brit is the second violinist, a beautiful and quiet orphan; on the viola is Henry, a prodigy who's always had it easy; the cellist is Daniel, the oldest and an angry skeptic who sleeps around; and on first violin is Jana, their flinty, resilient leader. Together, they are the Van Ness Quartet. After the group's youthful, rocky start, they experience devastating failure and wild success, heartbreak and marriage, triumph and loss, betrayal and enduring loyalty. They are always tied to each other --- by career, by the intensity of their art, by the secrets they carry, by choosing each other over and over again.