Peter Caine, a cutthroat Manhattan defense attorney, worked ruthlessly to become the best at his job. On the surface, he is charming and handsome, but inside he is cold and heartless. He fights without remorse to acquit murderers, pedophiles and rapists. When Charlie Doyle, the daughter of the Manhattan DA --- and Peter’s former lover --- is murdered, Peter’s world is quickly sent into a tailspin. He becomes the prime suspect as the DA, a professional enemy of Peter’s, embarks on a witch hunt to avenge his daughter’s death, stopping at nothing to ensure Peter is found guilty of the murder. But the truth of who killed Charlie is more twisted and sinister than anyone could have imagined.

Sam James has spent years carefully crafting her reputation as the best psychologist at Typhlos, Manhattan's most challenging psychiatric institution. She believes if she can't save herself, she'll save someone else. It's this savior complex that serves her well in helping patients battle their inner demons, though it leads Sam down some dark paths and opens her eyes to her own mental turmoil. When Richard, a mysterious patient no other therapist wants to treat, is admitted to Typhlos, Sam is determined to unlock his secrets and his psyche. But she can't figure out why Richard appears to be so normal in a hospital filled with madness. As Sam gets pulled into Richard's twisted past, she can't help but analyze her own life, and what she discovers terrifies her.