Wealthy financier and connoisseur of crime Jessup Quincannon is dead, and famed detective Lillian Pentecost is under arrest for his murder. Willowjean “Will” Parker knows for a fact that her boss is innocent. She just doesn’t know if she can prove it. With Lillian locked away in New York’s infamous women’s prison, the House of D, Will is left to root out the real killer. Was it a member of Quincannon’s murder-obsessed Black Museum Club? His jilted lover? Or the mob hit-man who disappeared just after the shots were fired?

With the city barreling toward the trial of the century, Will is desperate to get her boss out from behind bars before her reputation is destroyed. Because the House of D is no kind place, especially for a woman with multiple sclerosis. Or one with so many enemies. Lillian needs to survive long enough to take the stand. With time running out on both sides of the prison walls, Will and Lillian must wager everything to uncover who put their thumb on the scales and a bullet in Quincannon’s head. Before Lady Justice brings her sword down, ending Pentecost and Parker's adventures once and for all.