Following a leave of absence, Assistant DA Alexandra Cooper meets Lucy, a young woman who testified years earlier at a landmark federal trial and now reveals that she was sexually assaulted by a prominent official during that time. Yet Lucy's isn't the only secret Alex must uncover, with rumors swirling about one colleague's abusive conduct behind closed doors and another's violent, mysterious collapse. As the seemingly disparate cases of her client, adversary and friend start to intertwine, Alex, along with NYPD detectives Mike Chapman and Mercer Wallace, finds herself in uncharted territory within Manhattan's Rockefeller University, a premier research institute, hospital and cornerstone of higher learning.