AN ITALIAN WIFE begins in turn-of-the-century Italy, when 14-year-old Josephine Rimaldi is forced into an arranged marriage to a man she doesn't know or love who is about to depart for America, where she later joins him. Bound by tradition, Josephine gives birth to seven children. The last, Valentina, is conceived in passion, born in secret and given up for adoption. Josephine spends the rest of her life searching for her lost child, keeping her secret even as her other children go off to war, get married and make their own mistakes.

“When I was little I believed in Jesus and Santa, spontaneous combustion, and the Loch Ness monster. Now I believe in science, statistics, and antibiotics.” So says 17-year-old Zac Meier during a long, grueling leukemia treatment in Perth, Australia. A loud blast of Lady Gaga alerts him to the presence of Mia, the angry, not-at-all-stoic cancer patient in the room next door. Once released, the two near-strangers can’t forget each other, even as they desperately try to resume normal lives.