Although still not quite a dog lover, Maggie Patterson meets with her new group of dog-loving friends for “Yappy Hour” every Friday night. Both she and her sister Rachel have put the past murderous summer behind them, with Rachel even securing a headline feature for the Wine & Bark in Doggie Day magazine. But when her sister comes down with a case of salmonella poisoning, Maggie is left to run the business in her absence. Even worse, Maggie overhears an argument between her friend Yolanda and Bonnie, who runs the Chic Chickie shop. Then poor Bonnie turns up dead. With evidence pilling up against Yolanda, the Roundup Crew is desperate to find the real killer and convince Maggie to investigate.

Every Friday night, the Roundup Crew, a group of dog-loving friends, meets at a neighborhood wine bar for Yappy Hour. When Rachel, the owner, mysteriously leaves town and asks her sister, Maggie, to run the bar in her absence, things get complicated fast. Maggie arrives to open up and finds a body sprawled on the floor, along with an incriminating letter with Rachel's name on it nearby. On impulse, she hides the letter from the hunky detective, Officer Brad Brooks, who is dispatched to the scene. When Rachel is declared the top suspect by the police, Maggie decides to investigate on her own.