From her downstairs apartment in suburban London, Emma has often overheard the everyday life of the seemingly perfect family upstairs --- Steph, Paul and teenage daughter Freya --- but has never got to know them. Until one day, she hears something that seizes her attention: Freya has vanished, and the police are questioning Steph and Paul about their life. Do either of you have any enemies? Anyone who might want to harm or threaten you? The effects of Freya's disappearance ripple outward, affecting not just her parents, but everyone who lives in the building, including Emma and local driving instructor Chris, who was the last person to see the teenager before she went missing.

As a child, Isabel Allende watched her mother, abandoned by her husband, provide for her three small children without “resources or voice.” She became a fierce and defiant little girl, determined to fight for the life her mother couldn’t have. As a young woman coming of age in the late 1960s, she rode the second wave of feminism. Among a tribe of like-minded female journalists, Allende for the first time felt comfortable in her own skin, as they wrote “with a knife between our teeth” about women’s issues. She has seen what the movement has accomplished in the course of her lifetime. And over the course of three passionate marriages, she has learned how to grow as a woman while having a partner, when to step away, and the rewards of embracing one’s sexuality.

Talia is being held at a correctional facility for adolescent girls in the forested mountains of Colombia after committing an impulsive act of violence that may or may not have been warranted. She urgently needs to get out and get back home to Bogotá, where her father and a plane ticket to the United States are waiting for her. If she misses her flight, she also might miss her chance to finally be reunited with her family. How this family came to occupy two different countries, two different worlds, comes into focus like twists of a kaleidoscope.

Emma loves her life. She’s the mother of a precocious kindergartener, married to her soulmate --- a loyal and loving police detective --- and has a rewarding career as a doctor at the local hospital. But everything comes crashing down when her son, Josh, is diagnosed with a rare form of cancer. Determined to save him, Emma makes the risky decision to sell opioids to fund the life-saving treatment he needs. But when somebody ends up dead, a lethal game of cat and mouse ensues, her own husband leading the chase. With her son’s life hanging in the balance, Emma is dragged into the dark world of drugs, lies and murder. Will the truth catch up to her before she can save Josh?

Martine is a genetically cloned replica made from Evelyn Caldwell’s award-winning research. She’s patient and gentle and obedient. She’s everything Evelyn swore she’d never be. And she’s having an affair with Evelyn’s husband. Now, the cheating bastard is dead, and both Caldwell wives have a mess to clean up. Good thing Evelyn Caldwell is used to getting her hands dirty.

Fifteen-year-old equestrian prodigy Roan Montgomery has only ever known two worlds: inside the riding arena, and outside of it. Both, for as long as she can remember, have been ruled by her father, who demands strict obedience in all areas of her life. The warped power dynamic of coach and rider extends far beyond the stables, and Roan's relationship with her father has long been inappropriate. She has been able to compartmentalize that dark aspect of her life, ruthlessly focusing on her ambitions as a rider heading for the Olympics, just as her father had done. However, her developing relationship with Will Howard, a boy her own age, broadens the scope of her vision.

Teenage Eulabee and her magnetic best friend, Maria Fabiola, own the streets of Sea Cliff, their foggy oceanside San Francisco neighborhood. They know Sea Cliff’s homes and beaches, its hidden corners and eccentric characters --- as well as the upscale all-girls’ school they attend. One day, walking to school with friends, they witness a horrible act. Or do they? Eulabee and Maria Fabiola vehemently disagree on what happened, and their rupture is followed by Maria Fabiola’s sudden disappearance --- a potential kidnapping that shakes the quiet community and threatens to expose unspoken truths.

After losing both her parents, Zorrie moved in with her aunt, whose own death orphaned Zorrie all over again, casting her off into the perilous realities and sublime landscapes of rural, Depression-era Indiana. Drifting west, Zorrie survived on odd jobs, sleeping in barns and under the stars, before finding a position at a radium processing plant. At the end of each day, the girls at her factory glowed from the radioactive material. But when Indiana calls Zorrie home, she finally finds the love and community that have eluded her in and around the small town of Hillisburg. And yet, even as she tries to build a new life, Zorrie discovers that her trials have only begun.

Ruth Tuttle, an Ivy League-educated Black engineer, is married to a kind and successful man. He’s eager to start a family, but she's uncertain. She has never gotten over the baby she gave birth to --- and was forced to leave behind --- when she was a teenager. Returning home, Ruth discovers that the Indiana factory town of her youth is plagued by unemployment, racism and despair. As she begins digging into the past, she unexpectedly befriends Midnight, a young white boy who is also adrift and looking for connection. Just as Ruth is about to uncover a burning secret her family desperately wants to keep hidden, a traumatic incident strains the town’s already searing racial tensions, sending Ruth and Midnight on a collision course that could upend both their lives.

Every night, as Faye puts her daughters to bed, she thinks of her own mother, Jeanie, who died when she was eight. The pain of that loss has never left her, and that’s why she wants her own girls to know how very much they are loved by her --- and always will be, whatever happens. Then one day, Faye gets her heart’s desire when she is whisked back into the past and is reunited not just with her mother but with her own younger self. Jeanie doesn’t recognize grown-up Faye as her daughter, but the two women become close friends and share all kinds of secrets --- except for the deepest secret of all, the secret of who Faye really is. Faye worries that telling the truth may prevent her from being able to return to the present day, to her dear husband and beloved daughters.